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- Title
EAACI Biologicals Guidelines—dupilumab for children and adults with moderate‐to‐severe atopic dermatitis.
- Authors
Agache, Ioana; Akdis, Cezmi A.; Akdis, Mubeccel; Brockow, Knut; Chivato, Tomas; Giacco, Stefano; Eiwegger, Thomas; Eyerich, Kilian; Giménez‐Arnau, Ana; Gutermuth, Jan; Guttman‐Yassky, Emma; Maurer, Marcus; Ogg, Graham; Ong, Peck Y.; O'Mahony, Liam; Schwarze, Jürgen; Warner, Amena; Werfel, Thomas; Palomares, Oscar; Jutel, Marek
- Abstract
Atopic dermatitis imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care pathways and differences between national or regional healthcare systems. Better understanding of the mechanisms has enabled a stratified approach to the management of atopic dermatitis, supporting the use of targeted treatments with biologicals. However, there are still many issues that require further clarification. These include the definition of response, strategies to enhance the responder rate, the duration of treatment and its regimen (in the clinic or home‐based), its cost‐effectiveness and long‐term safety. The EAACI Guidelines on the use of dupilumab in atopic dermatitis follow the GRADE approach in formulating recommendations for each outcome and age group. In addition, future approaches and research priorities are discussed.
- Subjects
ATOPIC dermatitis; BIOLOGICALS; AGE groups; DUPILUMAB
- Publication
Allergy, 2021, Vol 76, Issue 4, p988
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.14690