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- Title
Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana Cream on the Skin Wound Infected with MRSA.
- Authors
Prakoso, Yos Adi; Setiyo Rini, Chylen; Wirjaatmadja, Roeswandono
- Abstract
The tropical area has a lot of herbal medicines such as <italic>Aloe vera</italic> (AV), <italic>Ananas comosus</italic> (AC), and <italic>Sansevieria masoniana</italic> (SM). All the three have a unique potential effect as an antibacterial and wound-healing promoter. The aim of this study is to explore the role of AV, AC, and SM on the skin wound infected with methicillin-resistant <italic>Staphylococcus aureus</italic> (MRSA). Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. All the groups were exposed to two round full-thickness punch biopsy and infected with MRSA. The group C was the control group/untreated; group BC was treated with base cream/without extract; group AV was treated with 75% AV cream; group AC was treated with 75% AC cream, and group SM was treated with 75% SM cream. The wounds were observed on days 5, 10, and 15. The healing of skin wounds was measured by a percentage of closure, skin tensile strength, and histopathology. The result showed that AV, AC, and SM have a similar potential effect on healing in the wound that was infected with MRSA compared to the groups C and BC (P<0.05). It shows that all the three herbal formulations can be used as the alternative therapy to the wound infected with MRSA.
- Subjects
SKIN injuries; SKIN infections; SANSEVIERIA; ALOE vera; PINEAPPLE; STAPHYLOCOCCUS aureus
- Publication
Advances in Pharmacological Sciences, 2018, p1
- ISSN
1687-6334
- Publication type
Article
- DOI
10.1155/2018/4670569