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Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.
- Published in:
- EMBO Journal, 2005, v. 24, n. 10, p. 1810, doi. 10.1038/sj.emboj.7600667
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- Publication type:
- Article
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.
- Published in:
- EMBO Journal, 2004, v. 23, n. 4, p. 833, doi. 10.1038/sj.emboj.7600110
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- Publication type:
- Article
Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.
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- EMBO Journal, 1998, v. 17, n. 6, p. 1688, doi. 10.1093/emboj/17.6.1688
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- Article
AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?
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- International Journal of Molecular Sciences, 2020, v. 21, n. 10, p. 3518, doi. 10.3390/ijms21103518
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- Article
AMP-activated protein kinase: the guardian of cardiac energy status.
- Published in:
- 2004
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- Publication type:
- journal article
AMP-activated protein kinase -- a journey from 1 to 100 downstream targets.
- Published in:
- Biochemical Journal, 2022, v. 479, n. 22, p. 2327, doi. 10.1042/BCJ20220255
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- Publication type:
- Article
Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity.
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- Biochemical Journal, 2018, v. 475, n. 18, p. 2969, doi. 10.1042/BCJ20180475
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- Publication type:
- Article
Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms.
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- Biochemical Journal, 2016, v. 473, n. 2, p. 189, doi. 10.1042/BJ20150910
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- Publication type:
- Article
PT-1 selectively activates AMPK-γ 1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain.
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- Biochemical Journal, 2015, v. 467, n. 3, p. 461, doi. 10.1042/BJ20141142
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- Publication type:
- Article
Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells.
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- Biochemical Journal, 2014, v. 459, n. 2, p. 275, doi. 10.1042/BJ20131344
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- Publication type:
- Article
Normal hypertrophy accompanied by phosphoryation and activation of AMP-activated protein kinase α1 following overload in LKB1 knockout mice.
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- Journal of Physiology, 2008, v. 586, n. 6, p. 1731, doi. 10.1113/jphysiol.2007.143685
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- Publication type:
- Article
De-phosphorylation of MyoD is linking nerve-evoked activity to fast myosin heavy chain expression in rodent adult skeletal muscle.
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- Journal of Physiology, 2007, v. 584, n. 2, p. 637, doi. 10.1113/jphysiol.2007.141457
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- Publication type:
- Article
AMP-activated protein kinase – development of the energy sensor concept.
- Published in:
- Journal of Physiology, 2006, v. 574, n. 1, p. 7, doi. 10.1113/jphysiol.2006.108944
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- Publication type:
- Article
Phenformin and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na<sup>+</sup> transport across H441 lung cells.
- Published in:
- Journal of Physiology, 2005, v. 566, n. 3, p. 781, doi. 10.1113/jphysiol.2005.088674
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- Publication type:
- Article
Regulation of hormone-sensitive lipase activity and Ser<sup>563</sup> and Ser<sup>565</sup> phosphorylation in human skeltal muscle during exercise.
- Published in:
- Journal of Physiology, 2004, v. 560, n. 2, p. 551, doi. 10.1113/jphysiol.2004.066480
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- Publication type:
- Article
Role of 5′AMP-activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease.
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- Journal of Physiology, 2002, v. 541, n. 3, p. 979, doi. 10.1113/jphysiol.2002.018044
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- Publication type:
- Article
SnRK1 (SNF1-related kinase 1) has a central role in sugar and ABA signalling in Arabidopsis thaliana.
- Published in:
- Plant Journal, 2009, v. 59, n. 2, p. 316, doi. 10.1111/j.1365-313X.2009.03871.x
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- Publication type:
- Article
Regulation of spinach SNF1-related (SnRK1) kinases by protein kinases and phosphatases is associated with phosphorylation of the T loop and is regulated by 5′-AMP.
- Published in:
- Plant Journal, 1999, v. 19, n. 4, p. 433, doi. 10.1046/j.1365-313X.1999.00532.x
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- Publication type:
- Article
The LKB1-AMPK-α1 signaling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria.
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- Science Signaling, 2018, v. 11, n. 550, p. 1, doi. 10.1126/scisignal.aau0296
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- Publication type:
- Article
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.
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- Nature Medicine, 2013, v. 19, n. 12, p. 1649, doi. 10.1038/nm.3372
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- Publication type:
- Article
Ion Channel Regulation by AMPK.
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- Annals of the New York Academy of Sciences, 2009, v. 1177, n. 1, p. 89, doi. 10.1111/j.1749-6632.2009.05041.x
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- Publication type:
- Article
AMP-Activated Protein Kinase: A Master Switch in Glucose and Lipid Metabolism.
- Published in:
- Reviews in Endocrine & Metabolic Disorders, 2004, v. 5, n. 2, p. 119
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- Publication type:
- Article
Ways of coping with stress.
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- Nature, 1994, v. 370, n. 6491, p. 599, doi. 10.1038/370599a0
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- Article
A new protein kinase cascade.
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- Nature Reviews Molecular Cell Biology, 2014, v. 15, n. 4, p. 223, doi. 10.1038/nrm3771
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- Article
AMPK: a nutrient and energy sensor that maintains energy homeostasis.
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- Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 4, p. 251, doi. 10.1038/nrm3311
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- Publication type:
- Article
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy.
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- Nature Reviews Molecular Cell Biology, 2007, v. 8, n. 10, p. 774, doi. 10.1038/nrm2249
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- Publication type:
- Article
Glycogen Content Regulates Peroxisome Proliferator Activated Receptor-∂ (PPAR-∂) Activity in Rat Skeletal Muscle.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077200
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- Article
AMPK and autophagy get connected.
- Published in:
- EMBO Journal, 2011, v. 30, n. 12, p. 2511, doi. 10.1038/emboj.2011.175
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- Publication type:
- Article
AMPK and autophagy get connected.
- Published in:
- EMBO Journal, 2011, v. 30, n. 4, p. 634, doi. 10.1038/emboj.2011.12
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- Publication type:
- Article
Regulation of AMP-activated protein kinase by a pseudosubstrate sequence on the γ subunit.
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- EMBO Journal, 2007, v. 26, n. 3, p. 806, doi. 10.1038/sj.emboj.7601542
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- Publication type:
- Article
Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade.
- Published in:
- Integrative Cancer Therapies, 2016, v. 15, n. 3, p. 376, doi. 10.1177/1534735415611747
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- Publication type:
- Article
Signal transduction: How cells sense energy.
- Published in:
- Nature, 2011, v. 472, n. 7342, p. 176, doi. 10.1038/472176a
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- Article
AMP-activated protein kinase: the energy charge hypothesis revisited.
- Published in:
- BioEssays, 2001, v. 23, n. 12, p. 1112, doi. 10.1002/bies.10009
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- Publication type:
- Article
AMP-activated protein kinase - An archetypal protein kinase cascade?
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- BioEssays, 1992, v. 14, n. 10, p. 699, doi. 10.1002/bies.950141011
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- Publication type:
- Article
Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism.
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- Proceedings of the Nutrition Society, 2011, v. 70, n. 1, p. 92, doi. 10.1017/S0029665110003915
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- Publication type:
- Article
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner.
- Published in:
- FASEB Journal, 2020, v. 34, n. 5, p. 6284, doi. 10.1096/fj.201903051R
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- Publication type:
- Article
Changes in mTOR/4‐EBP1 pathway induced by a novel mutation in PRKAG2 gene (864.7).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.864.7
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- Publication type:
- Article
Hot stuff: thyroid hormones and AMPK.
- Published in:
- Cell Research, 2010, v. 20, n. 12, p. 1282, doi. 10.1038/cr.2010.153
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- Publication type:
- Article
AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours.
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- FEBS Journal, 2016, v. 283, n. 16, p. 2987, doi. 10.1111/febs.13698
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- Publication type:
- Article
AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease.
- Published in:
- Journal of Internal Medicine, 2014, v. 276, n. 6, p. 543, doi. 10.1111/joim.12268
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- Publication type:
- Article
The pro-drug C13 activates AMPK by two distinct mechanisms.
- Published in:
- Biochemical Journal, 2024, v. 481, n. 18, p. 1203, doi. 10.1042/BCJ20240425
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- Publication type:
- Article
AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand.
- Published in:
- Biochemical Journal, 2024, v. 481, n. 8, p. 587, doi. 10.1042/BCJ20240082
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- Publication type:
- Article
Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers.
- Published in:
- Biochemical Journal, 2023, v. 480, n. 23, p. 1951, doi. 10.1042/BCJ20230380
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- Publication type:
- Article
Phenformin and AICAR decrease transepithelial Na+ transport across human H441 lung epithelial cells by different mechanisms.
- Published in:
- FASEB Journal, 2007, v. 21, n. 6, p. A954, doi. 10.1096/fasebj.21.6.a954-b
- By:
- Publication type:
- Article
LKB1 and AMPK and the cancer-metabolism link - ten years after.
- Published in:
- BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-36
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- Publication type:
- Article
AMPK: a cellular energy sensor primarily regulated by AMP.
- Published in:
- Biochemical Society Transactions, 2014, v. 42, n. 1, p. 71, doi. 10.1042/BST20130244
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- Publication type:
- Article
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
- Published in:
- Biochemical Society Transactions, 2013, v. 41, n. 2, p. 687, doi. 10.1042/BST20120351
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- Publication type:
- Article
5-Aminoimidazole-4-Carboxamide 1-β-D-Ribofuranoside Acutely Stimulates Skeletal Muscle 2-Deoxyglucose Uptake in Healthy Men.
- Published in:
- Diabetes, 2007, v. 56, n. 8, p. 2078, doi. 10.2337/db06-1716
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- Publication type:
- Article
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.
- Published in:
- 2004
- By:
- Publication type:
- journal article
The α2-5′ AMP-Activated Protein KinaseIs a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and IsResponsive to Glucose Loading.
- Published in:
- Diabetes, 2004, v. 53, n. 12, p. 3074, doi. 10.2337/diabetes.53.12.3074
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- Publication type:
- Article