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- Title
Early Mortality in Clinical Trials of Acute Respiratory Distress Syndrome.
- Authors
Giannakoulis, Vassilis G.; Schenck, Edward J.; Papoutsi, Eleni; Price, David R.; Villar, Jesús; Sarwath, Hina; Schmidt, Frank; Thompson, B. Taylor; Choi, Augustine M. K.; Siempos, Ilias I.
- Abstract
The article focuses on early mortality among patients with acute respiratory distress syndrome (ARDS) within the context of randomized controlled trials. It hypothesizes that early deaths, occurring within 3 days of randomization, exhibit distinct baseline characteristics, clinical trajectories, and proteomic profiles compared to late deaths. It highlight potential biomarkers associated with early mortality in ARDS, providing insights for prognosis and therapeutic strategies.
- Subjects
ADULT respiratory distress syndrome; CLINICAL trials; LACTOSE intolerance
- Publication
American Journal of Respiratory & Critical Care Medicine, 2024, Vol 210, Issue 2, p236
- ISSN
1073-449X
- Publication type
Letter
- DOI
10.1164/rccm.202402-0318LE