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- Title
ROLE OF CYTOKINES AND CHEMOKINES IN RENAL ISCHEMIA--REPERFUSION INJURY.
- Authors
Furuichi, Kengo; Wada, Takashi; Yokoyama, Hitoshi
- Abstract
Focuses on the contribution of the inflammatory cascade to renal ischemia--reperfusion injury. Information that cytokines and chemokines participate in leukocyte migration to the diseased kidney; Information that hydrogen peroxide, which is the oxygen free radicals leaded after reperfusion injury directly activates p38 mitogen-activated protein kinase (MAPK); Claim that p38 MAPK is one of the key molecules involved in chemokine/cytokine production, which brings about the initiation of inflammation after reperfusion injury.
- Subjects
REPERFUSION injury; CYTOKINES; ISCHEMIA; CHEMOKINES; HYDROGEN peroxide; LEUCOCYTES
- Publication
Current Medical Literature: Nephrology & Hypertension, 2005, Vol 11, Issue 1, p1
- ISSN
1357-1540
- Publication type
Article