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- Title
'Clickable' Hydrosoluble PEGylated Cryptophane as a Universal Platform for <sup>129</sup>Xe Magnetic Resonance Imaging Biosensors.
- Authors
Delacour, Léa; Kotera, Naoko; Traoré, Ténin; Garcia‐Argote, Sébastien; Puente, Céline; Leteurtre, François; Gravel, Edmond; Tassali, Nawal; Boutin, Céline; Léonce, Estelle; Boulard, Yves; Berthault, Patrick; Rousseau, Bernard
- Abstract
We describe the synthesis of a highly water-soluble cryptophane 1 that can be seen as a universal platform for the construction of 129Xe magnetic resonance imaging (MRI)-based biosensors. Compound 1 is easily functionalized by Huisgen cycloaddition and exhibits excellent xenon-encapsulation properties. In addition, 1 is nontoxic at the concentrations typically used for hyperpolarized 129Xe MRI.
- Publication
Chemistry - A European Journal, 2013, Vol 19, Issue 19, p6089
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201204218