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- Title
Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne.
- Authors
Jieru Guo; Jinwen Zhang; Penghua Shu; Lingmei Kong; Xincai Hao; Yongbo Xue; Zengwei Luo; Yan Li; Gao Li; Guangmin Yao; Yonghui Zhang
- Abstract
Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P2 (2), P3 (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (-)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10), were isolated from the buds of Wikstroemia chamaedaphne Meissn. Their structures were elucidated by a combination of spectroscopic analyses. Compounds 1-10 were evaluated for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines in vitro.
- Subjects
DITERPENES; LIGNANS; WIKSTROEMIA; PHENYL compounds; CELL-mediated cytotoxicity
- Publication
Molecules, 2012, Vol 17, Issue 6, p6424
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules17066424