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- Title
Identification and genome characterization of a novel picornavirus from ducks in China.
- Authors
Li, Yufeng; Wang, Kaicheng; Yu, Kexiang; Hu, Feng; Tian, Xue; Huang, Bing; Liu, Hualei; Wu, Jiaqiang; Song, Minxun
- Abstract
A novel picornavirus, referred to as Duck/FC22/China/2017, was isolated from breeding ducks in China and genetically characterized by conducting metagenomics studies. The complete genome consists of a single-stranded, positive-sense RNA made up of 7448 nucleotides (nt) and follows the common picornavirus genome layout: 5′ UTR-VP0-VP3-VP1-2A-2B-2C-3A-3B-3C-3D-3′ UTR. A typical type-IV internal ribosomal entry site and a conserved 'barbell-like' structure were identified in the 5′ UTR and 3′ UTR, respectively. The unique 6423-nt open reading frame was predicted to encode a 2141-amino-acid (aa) polyprotein precursor. A pairwise aa sequence identity comparison and phylogenetic analysis revealed that Duck/FC22/China/2017 is closely related to duck aalivirus, duck hepatitis A virus, turkey avisivirus, and red-crowned crane picornavirus.
- Subjects
DUCK plague; HEPATITIS A virus; IDENTIFICATION
- Publication
Archives of Virology, 2020, Vol 165, Issue 9, p2087
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s00705-020-04691-7