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- Title
Heterogeneity: Explosive beginnings.
- Authors
Alderton, Gemma K.
- Abstract
The article discuses the study "A Big Bang model of Human Colorectal Tumor Growth," by researcher A. Sottoriva and colleagues, and published in the journal "Nature Genetics," which reveal spatial patterns of Intratumoural Heterogeneity (ITH) and the underlying clonal dynamics. Topics discussed include results of the analysis of multiple single glands and bulk tumour regions in colorectal tumours, model of tumour initiation in colorectal cancer and assessing spatial heterogeneity within glands.
- Subjects
COLON cancer; SOTTORIVA, A.; TUMOR growth; HETEROGENEITY; NATURE Genetics (Periodical)
- Publication
Nature Reviews Cancer, 2015, Vol 15, Issue 4, p198
- ISSN
1474-175X
- Publication type
Article
- DOI
10.1038/nrc3928