The article discusses research being done on the use of incorrect posttranslational modification to make tumor-specific antigens. It references a study by Schietinger et al published in a 2006 issue of the journal "Science." The study reveals that mutation is not needed in the antigen itself to make it tumor specific. In addition to Cosmc mutations in a human colon cancer and a T cell leukemia cell line, the team discovered that Cosmc was also mutated in a murine neuroblastoma.