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- Title
Labordiagnostik bei der Insektengift-Allergie.
- Authors
Reimers, Andrea; Müller, U.
- Abstract
Beside patient history and skin tests, laboratory investigations are the third pillar for the diagnosis of insect venom allergy. The correct diagnosis is decisive for the indication for specific immunotherapy with the respective insect venom. Specific serum IgE to honey bee and wasp venom are routinely measured. Other more laborious laboratory investigations are based on the estimation of mediators released from allergen-stimulated blood basophils or the activation of these cells, as indicated by CD 63 expression after allergen contact. Venom-specific IgG and immunoblots may be used in the follow-up of immunotherapy. Inhibition tests are valuable in the differentiation between multiple sensitization and crossreactivity. The estimation of basal serum tryptase may be indirectly helpful, especially for risk evaluation.
- Publication
Journal of Laboratory Medicine / Laboratoriums Medizin, 2002, Vol 26, Issue 3/4, p115
- ISSN
0342-3026
- Publication type
Article