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- Title
Special Issue on "Pharmacodynamics Modeling of Anti-Inflammatory Drugs".
- Authors
Kim, Jai-Eun; Oh, Myung Sook; Park, Wansu
- Abstract
In addition, although animal experiments have not provided confirmation, ER stress signaling is modulated by the inhibition of intracellular calcium release through the regulation of p38 MAPK phosphorylation and the expression of the transcription factor CHOP. In respiratory infectious diseases such as COVID-19, cytokine overproduction, called "cytokine storms", is a problem, but the detailed mechanism of cytokine storms has not yet been fully identified. For example, the hyperinflammation caused by respiratory infections (e.g., cytokine storm) exacerbates lung damage and is associated with acute respiratory distress syndrome.
- Subjects
MACROPHAGE colony-stimulating factor; ANTI-inflammatory agents; ENDOPLASMIC reticulum; INTRACELLULAR calcium; DISEASE risk factors; PHARMACODYNAMICS; GRANULOCYTE-macrophage colony-stimulating factor
- Publication
Processes, 2023, Vol 11, Issue 7, p2083
- ISSN
2227-9717
- Publication type
Article
- DOI
10.3390/pr11072083