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- Title
Choroidal thickness outside the laser irradiation area after photodynamic therapy in polypoidal choroidal vasculopathy.
- Authors
Sugano, Yukinori; Iida, Tomohiro; Maruko, Ichiro; Ojima, Akira; Sekiryu, Tetsuju
- Abstract
Purpose: To evaluate changes in choroidal thickness adjacent to the area of laser application after photodynamic therapy (PDT) in patients with polypoidal choroidal vasculopathy (PCV) using enhanced depth imaging spectral-domain optical coherence tomography. Methods: Masked observers measured the choroidal thickness at the subfovea and superior, inferior and temporal areas adjacent to the area of laser application before, 2 days, 1 week and 1 and 3 months after treatment. Results: Thirty-seven patients with PCV treated with PDT with verteporfin were included. The mean subfoveal choroidal thickness decreased significantly ( P < 0.001) from 256 ± 115 μm at baseline to 207 ± 111 μm at 3 months; the mean outside choroidal thickness including the superior, inferior and temporal areas decreased significantly ( P < 0.001) from 240 ± 92 μm at baseline to 209 ± 86 μm at 3 months. Conclusion: PDT affected not only the subfoveal choroid, but also the choroid outside the area of laser application in PCV.
- Subjects
PHOTOCHEMOTHERAPY; TOMOGRAPHY; INDUSTRIAL lasers; PHOTOTHERAPY; RADIOSCOPIC diagnosis
- Publication
Japanese Journal of Ophthalmology, 2013, Vol 57, Issue 3, p294
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-013-0230-3