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- Title
Progressive multifocal leukoencephalopathy in a renal transplant patient.
- Authors
Lin, Tsu-Chen; Wu, Mei-Yi; Luh, Hui-Tzung; Lin, Shiou-Fu; Lin, Chien-Min; Tseng, Ying-Chi; Liu, Yung-Ching; Wu, Mai-Szu
- Abstract
End-stage renal disease (ESRD) has a major impact on health and affects more than 600,000 people in the USA. The current mainstay treatments include dialysis and kidney transplantation (KT), and patients who have received KT have a higher quality of life and a lower mortality risk than those on chronic dialysis. Therefore, KT is considered the more preferred treatment modality for patients with ESRD. However, even though KT results in a higher long-term survival rate, the use of immunosuppressants is associated with various complications, including opportunistic infections and malignancies, which may lead to a higher risk of death in the first year after transplantation. Progressive multifocal leukoencephalopathy (PML) is a rare complication following KT, with an incidence of 0.027% in KT recipients. We present a case of PML following immunosuppressant therapy in a patient who received KT.
- Subjects
UNITED States; PROGRESSIVE multifocal leukoencephalopathy; NATALIZUMAB; KIDNEY transplantation; CHRONIC kidney failure; OPPORTUNISTIC infections; HEMODIALYSIS
- Publication
Journal of NeuroVirology, 2019, Vol 25, Issue 4, p612
- ISSN
1355-0284
- Publication type
Article
- DOI
10.1007/s13365-019-00749-8