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- Title
Non-Gaussian diffusion MRI of gray matter is associated with cognitive impairment in multiple sclerosis.
- Authors
Bester, M; Jensen, JH; Babb, JS; Tabesh, A; Miles, L; Herbert, J; Grossman, RI; Inglese, M
- Abstract
The article presents a study which examines the association of non-Gaussian diffusion magnetic resonance imaging (MRI) of gray matter (GM) with cognitive deficits in patients with multiple sclerosis (MS). The study is investigated by histogram analysis, Spearman rank correlations, and MRI. Results show that mean kurtosis (MK) was associated with cognitive impairment in MS patients and diffusional kurtosis imaging (DKI) can be use as biomarker for cortical injury.
- Subjects
GAUSSIAN beams; MAGNETIC resonance imaging; GRAY matter (Nerve tissue); COGNITION disorders; MULTIPLE sclerosis; BIOMARKERS; HISTOGRAMS; RANK correlation (Statistics); PATIENTS
- Publication
Multiple Sclerosis Journal, 2015, Vol 21, Issue 7, p935
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458514556295