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- Title
The challenge of identifying cellular mechanisms of memory formation during sleep.
- Authors
Szymusiak, Ronald
- Abstract
Cellular mechanisms hypothesized to underlie sleep-dependent memory consolidation are expressed throughout the brain during sleep. Use of sleep deprivation to evaluate the functional importance of these mechanisms is confounded by degradation in waking performance resulting from impaired vigilance. There is a need for methods that will permit disruption of specific mechanisms during sleep only in the neuronal circuits most critically involved in learning. This should be accomplished without global sleep disruption and with preservation of the restorative aspects of sleep.
- Subjects
SLEEP deprivation; PHYSIOLOGICAL stress; BIOLOGICAL adaptation; SLEEP disorders; NEUROLOGICAL disorders; NEURAL circuitry
- Publication
Behavioral & Brain Sciences, 2005, Vol 28, Issue 1, p84
- ISSN
0140-525X
- Publication type
Article
- DOI
10.1017/S0140525X05420026