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- Title
Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.
- Authors
Alhadj Ali, Mohammad; Yuk-Fun Liu; Arif, Sefina; Tatovic, Danijela; Shariff, Hina; Gibson, Vivienne B.; Yusuf, Norkhairin; Baptista, Roman; Eichmann, Martin; Petrov, Nedyalko; Heck, Susanne; Yang, Jennie H. M.; Tree, Timothy I. M.; Pujol-Autonell, Irma; Yeo, Lorraine; Baumard, Lucas R.; Stenson, Rachel; Howell, Alex; Clark, Alison; Boult, Zoe
- Abstract
The article discusses on the immunotherapy using the proinsulin peptide in human with type 1 diabetes,citing its metabolic and immune effects. It cites on the development of immunomodulatory therapies. The article also discusses on the understanding the immunological pathways that contribute to beta cell loss.
- Subjects
PROINSULIN; PEPTIDES; TYPE 1 diabetes; IMMUNOTHERAPY; LEUCOCYTES
- Publication
Science Translational Medicine, 2017, Vol 9, Issue 402, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aaf7779