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- Title
Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy.
- Authors
Taku Fujimura; Kayo Tanita; Yota Sato; Yumi Kambayashi; Sadanori Furudate; Akira Tsukada; Akira Hashimoto; Setsuya Aiba
- Abstract
Mogamulizumab induces cytotoxicity against CCR4+ lymphoma cells by antibody-dependent cell-mediated cytotoxicity in advanced cutaneous T-cell lymphoma patients. Since the efficacy of mogamulizumab in mycosis fungoides (28.6%) is lower than that in Sézary syndrome (47.1%), reagents that enhance the antitumor immune response induced by mogamulizumab are needed to further optimize its use for the treatment of erythrodermic mycosis fungoides. In this report, we present a case of erythrodermic mycosis fungoides successfully treated with mogamulizumab followed by etoposide monotherapy.
- Subjects
MONOCLONAL antibodies; ETOPOSIDE
- Publication
Case Reports in Oncology, 2018, Vol 11, Issue 1, p29
- ISSN
1662-6575
- Publication type
Case Study
- DOI
10.1159/000486278