We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Updated Perspectives on Pulmonary Hypertension in COPD.
- Authors
Blanco, Isabel; Tura-Ceide, Olga; Peinado, Victor Ivo; Barberà, Joan Albert
- Abstract
Pulmonary hypertension (PH) is a frequent and important complication of chronic obstructive pulmonary disease (COPD). It is associated with worse clinical courses with more frequent exacerbation episodes, shorter survival, and greater need of health resources. PH is usually of moderate severity and progresses slowly, without altering right ventricular function in the majority of cases. Nevertheless, a reduced subgroup of patients may present disproportionate PH, with pulmonary artery pressure (PAP) largely exceeding the severity of respiratory impairment. These patients may represent a group with an exaggerated vascular impairment (pulmonary vascular phenotype) to factors that induce PH in COPD or be patients in whom idiopathic pulmonary arterial hypertension (PAH) coexist. The present review addresses the current definition and classification of PH in COPD, the distinction among the different phenotypes of pulmonary vascular disease that might present in COPD patients, and the therapeutic approach to PH in COPD based on the available scientific evidence.
- Publication
International Journal of COPD, 2020, Vol 16, p1315
- ISSN
1176-9106
- Publication type
Article
- DOI
10.2147/COPD.S211841