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- Title
Exploring associations between perinatal depression, anxiety, and urinary oxytocin levels in Latinas.
- Authors
Lara-Cinisomo, Sandraluz; D'Anna-Hernandez, Kimberly; Fujimoto, Elinor M.; Pedersen, Cort A.
- Abstract
Perinatal depression has been associated with lower oxytocin (OT) levels. However, few studies have explored this topic in relation to Latinas who are at high risk of perinatal depression. The objective of this study was to explore these associations in Latinas. A total of 108 Latinas in the third trimester of pregnancy participated in the study. Depression and urinary OT levels were assessed in pregnancy and 6 weeks postpartum. Nonparametric tests were implemented to test the proposed associations. Results revealed that 28% of the participants had probable depression in pregnancy, and 23% at 6 weeks postpartum. OT levels significantly decreased from prenatal to postpartum in the whole sample; however, participants with probable prenatal depression did not exhibit a significant change in OT levels. Participants who were depressed or anxious at 6 weeks postpartum exhibited persistently higher mean OT levels over time. A distinct pattern of higher levels of OT in depressed Latinas suggests that OT levels may be an important neuroendocrine factor contributing to depressive and anxious symptoms.
- Subjects
ANXIETY diagnosis; DIAGNOSIS of mental depression; MENTAL depression risk factors; ANXIETY risk factors; PSYCHOLOGY of Hispanic Americans; MATERNAL health services; OXYTOCIN; POSTNATAL care; THIRD trimester of pregnancy; PRENATAL care; RISK assessment; URINALYSIS; WOMEN'S health
- Publication
Archives of Women's Mental Health, 2019, Vol 22, Issue 4, p447
- ISSN
1434-1816
- Publication type
Article
- DOI
10.1007/s00737-018-0910-6