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- Title
bcr-ablHybrid Messenger RNA in a Patient with Philadelphia-Negative Essential Thrombocythemia.
- Authors
Hashino, Satoshi; Imamura, Masahiro; Kobayashi, Sumiko; Kunieda, Yasuyuki; Kobayashi, Hajime
- Abstract
We describe a case of Philadelphia-negative essential thrombocythemia in whom bcr-abl hybrid messenger RNA was detected. The patient suffered from frequent splenic infarctions and myelofibrosis. Interestingly, a transformation to acute leukemia which was commonly seen in patients with bcr-abl-positive. chronic myelogenous leukemia did not occur until he died from heart failure due to severe anemia 8 years after the diagnosis. The heterogeneity of bcr-abl- positiveessential thrombocythemia is emphasized. Copyright © 1995 S. Karger AG, Basel
- Publication
Acta Haematologica, 1995, Vol 94, Issue 1, p52
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000203972