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- Title
Relationship between Impulsivity and Serum Oxytocin in Male Children and Adolescents with Attention-Deficit and Hyperactivity Disorder: A Preliminary Study.
- Authors
DEMİRCİ, Esra; ÖZMEN, Sevgi; ÖZTOP, Didem Behice
- Abstract
Introduction: Here we aimed to determine the relationship between oxytocin levels and impulsivity, which is an important aspect at Attention Deficit Hyperactivity Disorder (ADHD) clinics. Methods: The study population comprised 40 ADHD patients diagnosed based on the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version, without other psychiatric disorders and chronic diseases aged between 8 and l5 years. The control group comprised 40 healthy, age-matched, male children and adolescents who voluntarily participated in the study. Patients and controls filled the Barratt impulsivity scale-II (BIS-II). Ten cubic centimeters of blood was collected at 8 am for determining serum oxytocin levels. ELISA kits were used to measure serum oxytocin levels in a biochemistry laboratory. The obtained data were evaluated using appropriate statistical methods. Results: In this study, compared with the control group, the impulsivity scores were significantly higher and serum oxytocin levels were lower in the ADHD group (52.5±18.1 and 37.62±9.0, respectively, p<0.00l). Serum oxytocin levels showed a negative correlation with impulsivity and attention subscale scores of BIS-II in the ADHD group. Conclusion: ADHD and impulsivity, which comprise an aspect of ADHD, may be associated with oxytocin. Serum oxytocin levels may contribute to inattention subtypes of impulsivity observed in ADHD.
- Subjects
AFFECTIVE disorders; ATTENTION-deficit hyperactivity disorder; ENZYME-linked immunosorbent assay; IMPULSE control disorders; OXYTOCIN; SCHIZOPHRENIA in children; CONTROL groups; DESCRIPTIVE statistics
- Publication
Archives of Neuropsychiatry / Nöropsikiyatri Arşivi, 2016, Vol 53, Issue 4, p291
- ISSN
1300-0667
- Publication type
Article
- DOI
10.5152/npa.2015.10284