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- Title
Bacteriological Differences Between COPD Exacerbation and Community-Acquired Pneumonia.
- Authors
Xue-Jun Li; Qi Li; Liang-Yi Si; Qiao-Ying Yuan
- Abstract
OBJECTIVE: To study the differences in pathogen distribution and antibiotic susceptibility between patients with COPD exacerbation and patients with community-acquired pneumonia, and develop guidance for antibiotic treatment of those conditions. METHODS: We retrospectively analyzed the medical records of 586 COPD-exacerbation patients and 345 community-acquired-pneumonia patients from January 2007 to December 2008, including sputum culture results, antibiotic susceptibilities of the microorganisms, and clinical characteristics. RESULTS: 276 (47%) of the COPD-exacerbation patients, and 183 (53%) of the community-acquired-pneumonia patients had a positive sputum culture. In order, the most common pathogens in the COPD-exacerbation patients were Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Acinetobacter baumannii, and Haemophilus influenzae. The most common pathogens in the community-acquired-pneumonia patients were Streptococcus pneumoniae, H. influenzae, K. pneumoniae, S. aureus, and E. coli. CONCLUSIONS: P. aeruginosa was the most common pathogen in our patients with COPD exacerbation, and S. pneumoniae was the most common in our patients with community-acquired pneumonia. P. aeruginosa is especially common in the patients with serious or extremely serious COPD.
- Subjects
CHINA; SPUTUM microbiology; ANTIBIOTICS; ACADEMIC medical centers; ANALYSIS of variance; CHI-squared test; DRUG resistance in microorganisms; OBSTRUCTIVE lung diseases; MICROBIOLOGICAL techniques; COMMUNITY-acquired pneumonia; RETROSPECTIVE studies; SEVERITY of illness index; DISEASE exacerbation; DATA analysis software
- Publication
Respiratory Care, 2011, Vol 56, Issue 11, p1818
- ISSN
0020-1324
- Publication type
Article
- DOI
10.4187/respcare.00915