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- Title
Magnetic and electric responsive hydrogel-magnetic nanocomposites for drug-delivery application.
- Authors
Reddy, N. Narayana; Mohan, Y. Murali; Varaprasad, K.; Ravindra, S.; Joy, P. A.; Raju, K. Mohana
- Abstract
Magnetic and electrically responsive hydrogel networks were developed for drug-delivery applications. The hydrogel matrices were synthesized by the polymerization of acrylamide monomer in the presence of carboxymethylcellulose (CMC) or methylcellulose (MC) with N,N-methylenebisacrylamide, a crosslinker with the redox initiating system ammonium persulfate/tetramethylethylenediamine. The magnetic nanoparticles were generated throughout these hydrogel matrices by an in situ method by the incorporation of iron ions and their subsequent reduction with ammonia. A series of hydrogel-magnetic nanocomposites (HGMNCs) were developed with various CMC and MC compositions. The synthesized HGMNCs were characterized with spectral (Fourier transform infrared and ultraviolet-visible spectroscopy), X-ray diffraction, thermal, and microscopy methods. These HGMNCs contained iron oxide (Fe
- Subjects
HYDROGELS; NANOCOMPOSITE materials; ACRYLAMIDE; AMMONIUM; NANOTECHNOLOGY; DRUG delivery systems; IRON ions
- Publication
Journal of Applied Polymer Science, 2011, Vol 122, Issue 2, p1364
- ISSN
0021-8995
- Publication type
Article
- DOI
10.1002/app.34016