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- Title
Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy.
- Authors
Bouchard, Josée; Madore, François
- Abstract
Anticoagulation is required during continuous renal replacement therapy to prevent filter clotting and optimize filter performance. However, anticoagulation may also be associated with serious bleeding complications. Patients with liver failure often suffer from underlying coagulopathy and are especially prone to anticoagulation complications. The aim of this review is to present the unique features of patients with hepatic injury in terms of anticoagulation disorders and to analyze data on safety and efficacy of the different anticoagulation methods for liver failure patients undergoing continuous renal replacement therapy.
- Subjects
CITRATES; LIVER failure; LIVER diseases; THERAPEUTICS; DISEASES
- Publication
NDT Plus, 2009, Vol 2, Issue 1, p11
- ISSN
1753-0784
- Publication type
Article
- DOI
10.1093/ndtplus/sfn184