We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of the steroid molecule structure on the direction of its hydroxylation by the fungus Curvularia lunata.
- Authors
Andryushina, V.; Yaderets, V.; Stytsenko, T.; Druzhinina, A.; Voishvillo, N.
- Abstract
The main and side products of hydroxylation by the C. lunata VKPM F-981 mycelium of fourteen Δ-3-ketosteroids of the estrane, androstane, and pregnane series and six of their Δ-3β-hydroxy analogues were identified by HPMR spectroscopy and comparison with standard samples. The obtained experimental data are considered in terms of the triangular model of the enzyme-substrate interaction. The dependence of the direction of hydroxylation of steroid molecules and the orientation of hydroxy groups on the structure of the initial substrate was revealed.
- Subjects
STEROIDS; HYDROXYLATION; MYCELIUM; ANDROSTANE; PREGNANE
- Publication
Applied Biochemistry & Microbiology, 2013, Vol 49, Issue 4, p386
- ISSN
0003-6838
- Publication type
Article
- DOI
10.1134/S0003683813040030