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- Title
Cure of intractable watery diarrhoea by excision of a vipoma.
- Authors
Modlin, Irvin M.; Bloom, Stephen R.; Barnes, A.; Welbourn, R. B.
- Abstract
A 56-year-old man suffered unexplained watery diarrhoea for 5 years which ultimately produced quadraparesis due to serve potassium depletion. All investigations were negative until demonstration of elevated plasma vasoactive intestinal peptide (VIP) indicated the presence of a vipoma. Removal of the VIP-producing tumour tissue-an adrenal ganglioneuroma-resulted in complete cure. Plasma VIP measurement is thus a valuable diagnostic screen in such cases and can be used to predict prognosis and to guide further therapy.
- Publication
British Journal of Surgery, 1978, Vol 65, Issue 4, p234
- ISSN
0007-1323
- Publication type
Article
- DOI
10.1002/bjs.1800650406