We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Biocatalytic Synthesis of Poly(δ-Valerolactone) Using a Thermophilic Esterase from Archaeoglobus fulgidus as Catalyst.
- Authors
Hong Cao; Haobo Han; Guangquan Li; Jiebing Yang; Lingfei Zhang; Yan Yang; Xuedong Fang; Quanshun Li
- Abstract
The ring-opening polymerization of δ-valerolactone catalyzed by a thermophilic esterase from the archaeon Archaeoglobus fulgidus was successfully conducted in organic solvents. The effects of enzyme concentration, temperature, reaction time and reaction medium on monomer conversion and product molecular weight were systematically evaluated. Through the optimization of reaction conditions, poly(δ-valerolactone) was produced in 97% monomer conversion, with a number-average molecular weight of 2225 g/mol, in toluene at 70 °C for 72 h. This paper has produced a new biocatalyst for the synthesis of poly(δ-valerolactone), and also deeper insight has been gained into the mechanism of thermophilic esterase-catalyzed ring-opening polymerization.
- Subjects
DELTA-valerolactone; ENZYMES; BIOSYNTHESIS; ARCHAEOGLOBUS fulgidus; THERMOPHILIC bacteria; CATALYSTS; RING formation (Chemistry); POLYMERIZATION
- Publication
International Journal of Molecular Sciences, 2012, Vol 13, Issue 10, p12232
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms131012232