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- Title
KAT's in the Cradle: p300/CBP and Regulation of HIF-1 and Blood Pressure during Intermittent Hypoxia.
- Authors
Shimoda, Larissa A.
- Abstract
The article focuses on the intricate regulation of the hypoxia-inducible factor 1 (HIF-1) pathway, particularly its modulation by intermittent hypoxia (IH) and its role in systemic blood pressure control. It explores the involvement of p300/CBP-mediated protein acetylation in IH-induced HIF-1 activation and suggests potential therapeutic targets for managing conditions such as hypertension associated with IH.
- Subjects
REGULATION of blood pressure; HYPOXEMIA
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2024, Vol 70, Issue 2, p87
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2023-0435ED