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- Title
Lessons from Listeria.
- Abstract
This article discusses pathogenicity associated with the bacteria Listeria. The bacterium is able to invade a host cell and manipulate cellular processes to move intra and intercellularly, resulting in the rapid spread of infection. While Listeria can move by means of flagella, this is not the primary means of movement at host body temperatures. Instead, the bacteria use host actin filaments to transport themselves through the host cytoplasm. Actin filaments form part of the cytoskeletal framework supporting many different types of cell extensions and cellular actinbased movement is important for neural outgrowth, intracellular vesicle movement, and a variety of other cellular processes.
- Subjects
LISTERIA; FOOD pathogens; ACTIN; CYTOPLASM; INFECTION; MEDICAL microbiology
- Publication
Nature Structural & Molecular Biology, 2005, Vol 12, Issue 1, p1
- ISSN
1545-9993
- Publication type
Editorial
- DOI
10.1038/nsmb0105-1