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- Title
PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.
- Authors
Jellinger, Kurt; Alafuzoff, Irina; Attems, Johannes; Beach, Thomas; Cairns, Nigel; Crary, John; Dickson, Dennis; Hof, Patrick; Hyman, Bradley; Jack, Clifford; Jicha, Gregory; Knopman, David; Kovacs, Gabor; Mackenzie, Ian; Masliah, Eliezer; Montine, Thomas; Nelson, Peter; Schmitt, Frederick; Schneider, Julie; Serrano-Pozo, Albert
- Abstract
The article discusses the relationship of primary age-related tauopathy (PART) with Alzheimer's disease (AD). It examines the hypothetical correlation between PART and AD. It mentions that PART is a neuropathological designation used to describe the neurofibrillary tangles that are commonly observed in the brains of elderly and individuals that can occur independently of the amyloid plaques of AD. It notes that PART do not meet the morphological criteria for sporadic AD.
- Subjects
AMYLOID plaque; ALZHEIMER'S disease; AMYLOID beta-protein; NEUROFIBRILLARY tangles; BASAL ganglia diseases
- Publication
Acta Neuropathologica, 2015, Vol 129, Issue 5, p757
- ISSN
0001-6322
- Publication type
Letter
- DOI
10.1007/s00401-015-1407-2