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- Title
Effects of manganese deficiency on serum hormones and biochemical markers of bone metabolism in chicks.
- Authors
Zhaojun, Wang; Lin, Wang; Zhenyong, Wang; Jian, Wang; Ran, Liu
- Abstract
In order to investigate the effect of manganese (Mn) deficiency on bone metabolism in chicks, ninety 1-day-old male Arbor Acre chicks were randomly divided into 3 groups and each group were given a diet having a different concentration of Mn (60 mg kg, control group; 40 mg kg, Mn-deficient group I; 8.7 mg kg, Mn-deficient group II). The serum was collected at 42 days old. Tests were performed to evaluate the changes in the levels of PTH, CT, ALP, TrACP, HOP TNF-alpha, OC, Mn and Ca in the serum of the chicks and the results showed that the levels of CT, ALP, TrACP, HOP, and Mn decreased markedly ( P < 0.05), while PTH, Ca, and TNF-alpha increased markedly ( P < 0.05) due to manganese deficiency in the diet, which indicates that Mn deficiency results in disorder of bone regulatory hormones and enzymes of bone metabolism in the serum.
- Subjects
MANGANESE in animal nutrition; MANGANESE in the body; BIOMARKERS; BLOOD serum analysis; HORMONES; BONE metabolism; CHICKENS as laboratory animals; CONTROL groups
- Publication
Journal of Bone & Mineral Metabolism, 2013, Vol 31, Issue 3, p285
- ISSN
0914-8779
- Publication type
Article
- DOI
10.1007/s00774-012-0417-6