We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Unique Imaging Features Enabling the Prenatal Diagnosis of Developmental Venous Anomalies: A Persistent Echogenic Brain Lesion Drained by a Collecting Vein in Contrast with Normal Brain Parenchyma on MRI.
- Authors
Haratz, Karina Krajden; Peled, Alon; Weizman, Boris; Gindes, Liat; Tamarkin, Mordechai; Lev, Dorit; Kidron, Dvora; Ben-Sira, Liat; Malinger, Gustavo; Lerman-Sagie, Tally; Leibovitz, Zvi; Krajden Haratz, Karina
- Abstract
<bold>Objective: </bold>To describe the prenatal imaging features enabling diagnosis of developmental venous anomalies (DVA).<bold>Methods: </bold>Four fetuses with unexplained persistent echogenic parenchymal brain lesions were studied. The evaluation included dedicated neurosonography, fetal MRI, serology for intrauterine infection, screening for coagulation abnormalities, and chromosomal microarray. Postnatal neurodevelopmental follow-up or autopsy results were assessed.<bold>Results: </bold>DVA presented as very slowly growing echogenic brain lesions without cystic components, calcifications, or structural changes on otherwise normal neurosonographic scans performed at 2- to 3-week intervals. A specific Doppler feature was a collecting vein draining the echogenic parenchyma. Fetal brain MRI depicted normal anatomy on half-Fourier acquisition single-shot turbo spin-echo and diffusion-weighted imaging. The rest of the evaluation was normal.<bold>Conclusions: </bold>In cases with a persistent, parenchymal echogenic lesion without clastic or structural changes, DVA should be considered. Demonstration of a collecting vein draining the lesion and normal brain anatomy on MRI confirm the diagnosis.
- Subjects
CHROMOSOMAL proteins; MAGNETIC resonance imaging; HUMAN abnormalities; CYSTIC fibrosis; FETAL brain abnormalities
- Publication
Fetal Diagnosis & Therapy, 2018, Vol 43, Issue 1, p53
- ISSN
1015-3837
- Publication type
journal article
- DOI
10.1159/000464247