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- Title
Protection for cyclists.
- Authors
Pickett, James
- Abstract
The article presents a study by A. A. Bicknell which shows the activation of unfolded protein response (UPR) by normal cell division. They stated that the activation of UPR would protect cells against fluctuations in endoplasmic reticulum (ER) demand. They studied the ER-stressed cells to discover the cause of the UPR activation. They also examined the UPR-defective yeast mutant strain to test if cytokinesis requires UPR activation. The results of the study was elaborated after the examination
- Subjects
DENATURATION of proteins; CELL division; BICKNELL, A. A.; ENDOPLASMIC reticulum; BIOTRANSFORMATION (Metabolism); CYTOKINESIS
- Publication
Nature Reviews Molecular Cell Biology, 2007, Vol 8, Issue 8, p600
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm2220