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- Title
Graft-Versus-Host Disease Associated Post-operative Complications After Pelvic Reconstructive Surgery: A Case Report.
- Authors
Chung, Christopher P.; Nademanee, Auayporn P.; Wakabayashi, Grace; Sadeghi, Maryam
- Abstract
Introduction: Graft-versus-host disease (GVHD) can occur after allogeneic bone marrow transplantation (BMT) and can affect the skin, gastrointestinal tract, lungs, liver, and vulvovaginal areas. Case Presentation: This case report described a 65-year-old multiparous patient with myelodysplastic syndrome who underwent a matched unrelated donor transplant approximately 3 years before her surgery. After her BMT she developed GVHD. She underwent anterior and posterior repair and uterosacral ligament suspension for stage III post-hysterectomy vaginal vault prolapse. Her postoperative course was complicated by mental status changes, abnormal liver function tests, and increasing abdominal distention. All her post-operative symptoms were resolved with conservative management. Conclusions: This case presentation highlights the potential atypical post-operative course of BMT patients with GVHD. The management of patients with GVHD relies heavily on the early involvement of hematologists.
- Subjects
SURGICAL complication risk factors; MENTAL illness risk factors; VAGINAL vault prolapse; MYELODYSPLASTIC syndromes; CONSERVATIVE treatment; GRAFT versus host disease; HYSTERECTOMY; BONE marrow transplantation; PLASTIC surgery; TREATMENT effectiveness; PELVIC organ prolapse; DISEASE complications
- Publication
International Journal of Cancer Management, 2022, Vol 15, Issue 9, p1
- ISSN
2538-4422
- Publication type
Article
- DOI
10.5812/ijcm-11594