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A mixed-model approach for powerful testing of genetic associations with cancer risk incorporating tumor characteristics.
Published in:
2021
By:
- Zhang, Haoyu;
- Zhao, Ni;
- Ahearn, Thomas U;
- Wheeler, William;
- García-Closas, Montserrat;
- Chatterjee, Nilanjan
Publication type:
journal article
Molecular mechanisms linking high body mass index to breast cancer etiology in post-menopausal breast tumor and tumor-adjacent tissues.
Published in:
Breast Cancer Research & Treatment, 2019, v. 173, n. 3, p. 667, doi. 10.1007/s10549-018-5034-1
By:
- Heng, Yujing J.;
- Wang, Jun;
- Ahearn, Thomas U.;
- Brown, Susan B.;
- Zhang, Xuehong;
- Ambrosone, Christine B.;
- de Andrade, Victor Piana;
- Brufsky, Adam M.;
- Couch, Fergus J.;
- King, Tari A.;
- Modugno, Francesmary;
- Vachon, Celine M.;
- DuPre, Natalie C.;
- Garcia-Closas, Montserrat;
- Troester, Melissa A.;
- Hunter, David J.;
- Eliassen, A. Heather;
- Tamimi, Rulla M.;
- Hankinson, Susan E.;
- Beck, Andrew H.
Publication type:
Article
Rare germline copy number variants (CNVs) and breast cancer risk.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02990-6
By:
- Dennis, Joe;
- Tyrer, Jonathan P.;
- Walker, Logan C.;
- Michailidou, Kyriaki;
- Dorling, Leila;
- Bolla, Manjeet K.;
- Wang, Qin;
- Ahearn, Thomas U.;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Antonenkova, Natalia N.;
- Arndt, Volker;
- Aronson, Kristan J.;
- Freeman, Laura E. Beane;
- Beckmann, Matthias W.;
- Behrens, Sabine;
- Benitez, Javier;
- Bermisheva, Marina;
- Bogdanova, Natalia V.;
- Bojesen, Stig E.
Publication type:
Article
Discovery of structural deletions in breast cancer predisposition genes using whole genome sequencing data from > 2000 women of African-ancestry.
Published in:
Human Genetics, 2021, v. 140, n. 10, p. 1449, doi. 10.1007/s00439-021-02342-8
By:
- Chen, Zhishan;
- Guo, Xingyi;
- Long, Jirong;
- Ping, Jie;
- Li, Bingshan;
- Fadden, Mary Kay;
- Ahearn, Thomas U.;
- Stram, Daniel O.;
- Shu, Xiao-Ou;
- Jia, Guochong;
- Figueroa, Jonine;
- the Ghana Breast Health Study team;
- Adjei, Robertson;
- Afriyie, Lucy;
- Adjei, Anthony;
- Dedey, Florence;
- Vanderpuye, Verna;
- Okyne, Victoria;
- Ohene Oti, Naomi;
- Tay, Evelyn
Publication type:
Article
Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24327-x
By:
- Adedokun, Babatunde;
- Du, Zhaohui;
- Gao, Guimin;
- Ahearn, Thomas U.;
- Lunetta, Kathryn L.;
- Zirpoli, Gary;
- Figueroa, Jonine;
- John, Esther M.;
- Bernstein, Leslie;
- Zheng, Wei;
- Hu, Jennifer J.;
- Ziegler, Regina G.;
- Nyante, Sarah;
- Bandera, Elisa V.;
- Ingles, Sue A.;
- Press, Michael F.;
- Deming-Halverson, Sandra L.;
- Rodriguez-Gil, Jorge L.;
- Yao, Song;
- Ogundiran, Temidayo O.
Publication type:
Article
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-022-01152-5
By:
- Mueller, Stefanie H.;
- Lai, Alvina G.;
- Valkovskaya, Maria;
- Michailidou, Kyriaki;
- Bolla, Manjeet K.;
- Wang, Qin;
- Dennis, Joe;
- Lush, Michael;
- Abu-Ful, Zomoruda;
- Ahearn, Thomas U.;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Antonenkova, Natalia N.;
- Arndt, Volker;
- Aronson, Kristan J.;
- Augustinsson, Annelie;
- Baert, Thais;
- Freeman, Laura E. Beane;
- Beckmann, Matthias W.;
- Behrens, Sabine
Publication type:
Article
Breast cancer risks associated with missense variants in breast cancer susceptibility genes.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01052-8
By:
- Dorling, Leila;
- Carvalho, Sara;
- Allen, Jamie;
- Parsons, Michael T.;
- Fortuno, Cristina;
- González-Neira, Anna;
- Heijl, Stephan M.;
- Adank, Muriel A.;
- Ahearn, Thomas U.;
- Andrulis, Irene L.;
- Auvinen, Päivi;
- Becher, Heiko;
- Beckmann, Matthias W.;
- Behrens, Sabine;
- Bermisheva, Marina;
- Bogdanova, Natalia V.;
- Bojesen, Stig E.;
- Bolla, Manjeet K.;
- Bremer, Michael;
- Briceno, Ignacio
Publication type:
Article
Calcium-Sensing Receptor Tumor Expression and Lethal Prostate Cancer Progression.
Published in:
2016
By:
- Ahearn, Thomas U;
- Tchrakian, Nairi;
- Wilson, Kathryn M;
- Lis, Rosina;
- Nuttall, Elizabeth;
- Sesso, Howard D;
- Loda, Massimo;
- Giovannucci, Edward;
- Mucci, Lorelei A;
- Finn, Stephen;
- Shui, Irene M
Publication type:
journal article
Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study.
Published in:
2022
By:
- Geczik, Ashley M.;
- Falk, Roni T.;
- Xu, Xia;
- Ansong, Daniel;
- Yarney, Joel;
- Wiafe-Addai, Beatrice;
- Edusei, Lawrence;
- Dedey, Florence;
- Vanderpuye, Verna;
- Titiloye, Nicholas;
- Adjei, Ernest;
- Aitpillah, Francis;
- Osei-Bonsu, Ernest;
- Oppong, Joseph;
- Biritwum, Richard;
- Nyarko, Kofi;
- Wiafe, Seth;
- Awuah, Baffour;
- Clegg-Lamptey, Joe-Nat;
- Ahearn, Thomas U.
Publication type:
journal article
Common variants in breast cancer risk loci predispose to distinct tumor subtypes.
Published in:
2022
By:
- Ahearn, Thomas U.;
- Zhang, Haoyu;
- Michailidou, Kyriaki;
- Milne, Roger L.;
- Bolla, Manjeet K.;
- Dennis, Joe;
- Dunning, Alison M.;
- Lush, Michael;
- Wang, Qin;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Arndt, Volker;
- Aronson, Kristan J.;
- Auer, Paul L.;
- Augustinsson, Annelie;
- Baten, Adinda;
- Becher, Heiko;
- Behrens, Sabine;
- Benitez, Javier;
- Bermisheva, Marina
Publication type:
journal article
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.
Published in:
2021
By:
- Morra, Anna;
- Escala-Garcia, Maria;
- Beesley, Jonathan;
- Keeman, Renske;
- Canisius, Sander;
- Ahearn, Thomas U.;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Arndt, Volker;
- Auer, Paul L.;
- Augustinsson, Annelie;
- Beane Freeman, Laura E.;
- Becher, Heiko;
- Beckmann, Matthias W.;
- Behrens, Sabine;
- Bojesen, Stig E.;
- Bolla, Manjeet K.;
- Brenner, Hermann;
- Brüning, Thomas;
- Buys, Saundra S.
Publication type:
journal article
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases.
Published in:
Cancers, 2023, v. 15, n. 13, p. 3313, doi. 10.3390/cancers15133313
By:
- Figlioli, Gisella;
- Billaud, Amandine;
- Wang, Qin;
- Bolla, Manjeet K.;
- Dennis, Joe;
- Lush, Michael;
- Kvist, Anders;
- Adank, Muriel A.;
- Ahearn, Thomas U.;
- Antonenkova, Natalia N.;
- Auvinen, Päivi;
- Behrens, Sabine;
- Bermisheva, Marina;
- Bogdanova, Natalia V.;
- Bojesen, Stig E.;
- Bonanni, Bernardo;
- Brüning, Thomas;
- Camp, Nicola J.;
- Campbell, Archie;
- Castelao, Jose E.
Publication type:
Article
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65665-y
By:
- Liu, Jingjing;
- Prager - van der Smissen, Wendy J. C.;
- Collée, J. Margriet;
- Bolla, Manjeet K.;
- Wang, Qin;
- Michailidou, Kyriaki;
- Dennis, Joe;
- Ahearn, Thomas U.;
- Aittomäki, Kristiina;
- Ambrosone, Christine B.;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Antonenkova, Natalia N.;
- Arndt, Volker;
- Arnold, Norbert;
- Aronson, Kristan J.;
- Augustinsson, Annelie;
- Auvinen, Päivi;
- Becher, Heiko;
- Beckmann, Matthias W.
Publication type:
Article
The oral microbiome and breast cancer and nonmalignant breast disease, and its relationship with the fecal microbiome in the Ghana Breast Health Study.
Published in:
International Journal of Cancer, 2022, v. 151, n. 8, p. 1248, doi. 10.1002/ijc.34145
By:
- Wu, Zeni;
- Byrd, Doratha A.;
- Wan, Yunhu;
- Ansong, Daniel;
- Clegg‐Lamptey, Joe‐Nat;
- Wiafe‐Addai, Beatrice;
- Edusei, Lawrence;
- Adjei, Ernest;
- Titiloye, Nicholas;
- Dedey, Florence;
- Aitpillah, Francis;
- Oppong, Joseph;
- Vanderpuye, Verna;
- Osei‐Bonsu, Ernest;
- Dagnall, Casey L.;
- Jones, Kristine;
- Hutchinson, Amy;
- Hicks, Belynda D.;
- Ahearn, Thomas U.;
- Shi, Jianxin
Publication type:
Article
Moving Toward Findable, Accessible, Interoperable, Reusable Practices in Epidemiologic Research.
Published in:
American Journal of Epidemiology, 2023, v. 192, n. 6, p. 995, doi. 10.1093/aje/kwad040
By:
- García-Closas, Montserrat;
- Ahearn, Thomas U;
- Gaudet, Mia M;
- Hurson, Amber N;
- Balasubramanian, Jeya Balaji;
- Choudhury, Parichoy Pal;
- Gerlanc, Nicole M;
- Patel, Bhaumik;
- Russ, Daniel;
- Abubakar, Mustapha;
- Freedman, Neal D;
- Wong, Wendy S W;
- Chanock, Stephen J;
- Gonzalez, Amy Berrington de;
- Almeida, Jonas S
Publication type:
Article
Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease.
Published in:
Carcinogenesis, 2018, v. 39, n. 12, p. 1431, doi. 10.1093/carcin/bgy112
By:
- Ahearn, Thomas U;
- Peisch, Sam;
- Pettersson, Andreas;
- Ebot, Ericka M;
- Zhou, Cindy Ke;
- Graff, Rebecca E;
- Sinnott, Jennifer A;
- Fazli, Ladan;
- Judson, Gregory L;
- Bismar, Tarek A;
- Rider, Jennifer R;
- Gerke, Travis;
- Chan, June M;
- Fiorentino, Michelangelo;
- Flavin, Richard;
- Sesso, Howard D;
- Finn, Stephen;
- Giovannucci, Edward L;
- Gleave, Martin;
- Loda, Massimo
Publication type:
Article
Pre-diagnostic circulating sex hormone levels and risk of prostate cancer by ERG tumour protein expression.
Published in:
2016
By:
- Graff, Rebecca E;
- Meisner, Allison;
- Ahearn, Thomas U;
- Fiorentino, Michelangelo;
- Loda, Massimo;
- Giovannucci, Edward L;
- Mucci, Lorelei A;
- Pettersson, Andreas
Publication type:
journal article
Circulating Antioxidant Levels and Risk of Prostate Cancer by TMPRSS2:ERG.
Published in:
Prostate, 2017, v. 77, n. 6, p. 647, doi. 10.1002/pros.23312
By:
- Graff, Rebecca E.;
- Judson, Gregory;
- Ahearn, Thomas U.;
- Fiorentino, Michelangelo;
- Loda, Massimo;
- Giovannucci, Edward L.;
- Mucci, Lorelei A.;
- Pettersson, Andreas
Publication type:
Article
Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach.
Published in:
Human Molecular Genetics, 2022, v. 31, n. 18, p. 3133, doi. 10.1093/hmg/ddac102
By:
- Gao, Guimin;
- Zhao, Fangyuan;
- Ahearn, Thomas U;
- Lunetta, Kathryn L;
- Troester, Melissa A;
- Du, Zhaohui;
- Ogundiran, Temidayo O;
- Ojengbede, Oladosu;
- Blot, William;
- Nathanson, Katherine L;
- Domchek, Susan M;
- Nemesure, Barbara;
- Hennis, Anselm;
- Ambs, Stefan;
- McClellan, Julian;
- Nie, Mark;
- Bertrand, Kimberly;
- Zirpoli, Gary;
- Yao, Song;
- Olshan, Andrew F
Publication type:
Article
Family history of prostate cancer and the incidence of ERG‐ and phosphatase and tensin homolog‐defined prostate cancer.
Published in:
International Journal of Cancer, 2020, v. 146, n. 10, p. 2694, doi. 10.1002/ijc.32577
By:
- Hashim, Dana;
- Gonzalez‐Feliciano, Amparo G.;
- Ahearn, Thomas U.;
- Pettersson, Andreas;
- Barber, Lauren;
- Pernar, Claire H.;
- Ebot, Ericka M.;
- Isikbay, Masis;
- Finn, Stephen P.;
- Giovannucci, Edward L.;
- Lis, Rosina T.;
- Loda, Massimo;
- Parmigiani, Giovanni;
- Lotan, Tamara;
- Kantoff, Philip W.;
- Mucci, Lorelei A.;
- Graff, Rebecca E.
Publication type:
Article
Weight change, obesity and risk of prostate cancer progression among men with clinically localized prostate cancer.
Published in:
International Journal of Cancer, 2017, v. 141, n. 5, p. 933, doi. 10.1002/ijc.30803
By:
- Dickerman, Barbra A.;
- Ahearn, Thomas U.;
- Giovannucci, Edward;
- Stampfer, Meir J.;
- Nguyen, Paul L.;
- Mucci, Lorelei A.;
- Wilson, Kathryn M.
Publication type:
Article
Mendelian randomisation study of smoking exposure in relation to breast cancer risk.
Published in:
2021
By:
- Park, Hanla A.;
- Neumeyer, Sonja;
- Michailidou, Kyriaki;
- Bolla, Manjeet K.;
- Wang, Qin;
- Dennis, Joe;
- Ahearn, Thomas U.;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Antonenkova, Natalia N.;
- Arndt, Volker;
- Aronson, Kristan J.;
- Augustinsson, Annelie;
- Baten, Adinda;
- Beane Freeman, Laura E.;
- Becher, Heiko;
- Beckmann, Matthias W.;
- Behrens, Sabine;
- Benitez, Javier;
- Bermisheva, Marina
Publication type:
journal article
Transforming growth factors and receptor as potential modifiable pre-neoplastic biomarkers of risk for colorectal neoplasms.
Published in:
Molecular Carcinogenesis, 2015, v. 54, n. 9, p. 821, doi. 10.1002/mc.22152
By:
- Tu, Huakang;
- Ahearn, Thomas U.;
- Daniel, Carrie R.;
- Gonzalez‐Feliciano, Amparo G.;
- Seabrook, March E.;
- Bostick, Roberd M.
Publication type:
Article
Effects of calcium and vitamin D<sub>3</sub> on transforming growth factors in rectal mucosa of sporadic colorectal adenoma patients: A randomized controlled trial.
Published in:
Molecular Carcinogenesis, 2015, v. 54, n. 4, p. 270, doi. 10.1002/mc.22096
By:
- Tu, Huakang;
- Flanders, W. Dana;
- Ahearn, Thomas U.;
- Daniel, Carrie R.;
- Gonzalez‐Feliciano, Amparo G.;
- Long, Qi;
- Rutherford, Robin E.;
- Bostick, Roberd M.
Publication type:
Article
Effects of calcium and vitamin D supplementation on crypt morphology in normal colon mucosa: A randomized clinical trial.
Published in:
Molecular Carcinogenesis, 2015, v. 54, n. 3, p. 242, doi. 10.1002/mc.22090
By:
- Shen, Huafeng;
- Ahearn, Thomas U.;
- Bostick, Roberd M.
Publication type:
Article
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00219-7
By:
- Ahuno, Samuel Terkper;
- Doebley, Anna-Lisa;
- Ahearn, Thomas U.;
- Yarney, Joel;
- Titiloye, Nicholas;
- Hamel, Nancy;
- Adjei, Ernest;
- Clegg-Lamptey, Joe-Nat;
- Edusei, Lawrence;
- Awuah, Baffour;
- Song, Xiaoyu;
- Vanderpuye, Verna;
- Abubakar, Mustapha;
- Duggan, Maire;
- Stover, Daniel G.;
- Nyarko, Kofi;
- Bartlett, John M. S.;
- Aitpillah, Francis;
- Ansong, Daniel;
- Gardner, Kevin L.
Publication type:
Article
PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants.
Published in:
NPJ Breast Cancer, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41523-023-00546-x
By:
- Muranen, Taru A.;
- Morra, Anna;
- Khan, Sofia;
- Barnes, Daniel R.;
- Bolla, Manjeet K.;
- Dennis, Joe;
- Keeman, Renske;
- Leslie, Goska;
- Parsons, Michael T.;
- Wang, Qin;
- Ahearn, Thomas U.;
- Aittomäki, Kristiina;
- Andrulis, Irene L.;
- Arun, Banu K.;
- Behrens, Sabine;
- Bialkowska, Katarzyna;
- Bojesen, Stig E.;
- Camp, Nicola J.;
- Chang-Claude, Jenny;
- Czene, Kamila
Publication type:
Article
The sequence kernel association test for multicategorical outcomes.
Published in:
Genetic Epidemiology, 2023, v. 47, n. 6, p. 432, doi. 10.1002/gepi.22527
By:
- Jiang, Zhiwen;
- Zhang, Haoyu;
- Ahearn, Thomas U.;
- Garcia‐Closas, Montserrat;
- Chatterjee, Nilanjan;
- Zhu, Hongtu;
- Zhan, Xiang;
- Zhao, Ni
Publication type:
Article
Distinct Reproductive Risk Profiles for Intrinsic-Like Breast Cancer Subtypes: Pooled Analysis of Population-Based Studies.
Published in:
JNCI: Journal of the National Cancer Institute, 2022, v. 114, n. 12, p. 1706, doi. 10.1093/jnci/djac117
By:
- Jung, Audrey Y;
- Ahearn, Thomas U;
- Behrens, Sabine;
- Middha, Pooja;
- Bolla, Manjeet K;
- Wang, Qin;
- Arndt, Volker;
- Aronson, Kristan J;
- Augustinsson, Annelie;
- Freeman, Laura E Beane;
- Becher, Heiko;
- Brenner, Hermann;
- Canzian, Federico;
- Carey, Lisa A;
- Consortium, CTS;
- Czene, Kamila;
- Eliassen, A Heather;
- Eriksson, Mikael;
- Evans, D Gareth;
- Figueroa, Jonine D
Publication type:
Article
A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer.
Published in:
2016
By:
- Ahearn, Thomas U.;
- Pettersson, Andreas;
- Ebot, Ericka M.;
- Gerke, Travis;
- Graff, Rebecca E.;
- Morais, Carlos L.;
- Hicks, Jessica L.;
- Wilson, Kathryn M.;
- Rider, Jennifer R.;
- Sesso, Howard D.;
- Fiorentino, Michelangelo;
- Flavin, Richard;
- Finn, Stephen;
- Giovannucci, Edward L.;
- Loda, Massimo;
- Stampfer, Meir J.;
- Marzo, Angelo M. De;
- Mucci, Lorelei A.;
- Lot, Tamara L.;
- De Marzo, Angelo M
Publication type:
journal article
Mosquito control exposures and breast cancer risk: analysis of 1071 cases and 2096 controls from the Ghana Breast Health Study.
Published in:
Breast Cancer Research, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13058-023-01737-x
By:
- Olivos, Naomie;
- Banta, Jim E.;
- Spencer-Hwang, Rhonda;
- Ansong, Daniel;
- Beane Freeman, Laura E.;
- Clegg-Lamptey, Joe-Nat;
- Wiafe-Addai, Beatrice;
- Edusei, Lawrence;
- Adjei, Ernest;
- Titiloye, Nicholas;
- Dedey, Florence;
- Aitpillah, Francis;
- Oppong, Joseph;
- Vanderpuye, Verna;
- Osei-Bonsu, Ernest;
- Ahearn, Thomas U.;
- Biritwum, Richard;
- Yarney, Joel;
- Awuah, Baffour;
- Nyarko, Kofi
Publication type:
Article
A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry.
Published in:
Breast Cancer Research, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13058-023-01691-8
By:
- Middha, Pooja;
- Wang, Xiaoliang;
- Behrens, Sabine;
- Bolla, Manjeet K.;
- Wang, Qin;
- Dennis, Joe;
- Michailidou, Kyriaki;
- Ahearn, Thomas U.;
- Andrulis, Irene L.;
- Anton-Culver, Hoda;
- Arndt, Volker;
- Aronson, Kristan J.;
- Auer, Paul L.;
- Augustinsson, Annelie;
- Baert, Thaïs;
- Freeman, Laura E. Beane;
- Becher, Heiko;
- Beckmann, Matthias W.;
- Benitez, Javier;
- Bojesen, Stig E.
Publication type:
Article

Found: 32