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- Title
Rasayana effect of Guduchi Churna on the life span of Drosophila melanogaster.
- Authors
Pathak, Pankaj; Vyas, Mahesh; Vyas, Hitesh; Naria, Mukesh
- Abstract
Introduction: The Drosophila melanogaster is one of the most extensively studied animal models for understanding the process of aging and longevity. This fly is being used for genetic studies since almost a century. Guduchi (Tinospora cordifolia [Wild.] Miers.) is an Ayurvedic drug used as Rasayana (rejuvenation) due to its antiaging effect. Aim: To explore the potential of Guduchi Churna (powder of T. cordifolia) on the life span of D. melanogaster using adult feeding method. Materials and Methods: For experimental setups, the regular food media were mixed with Guduchi Churna in different concentrations (0.25 g/100 ml, 0.50 g/100 ml, and 0.70 g/100 ml). Flies were exposed to these concentrations for 30 days. Results: Increase in the lifespan was observed in both parent and F-1 generation. Applying of ANOVA revealed significant difference between control and drug groups. The longevity effect, in the drug group was seen even on F-1 generation. Conclusion: Guduchi Churna enhances the life span of D. melanogaster in both parent and F-1 generation.
- Subjects
TINOSPORA cordifolia; DROSOPHILA melanogaster; LIFE spans; PHYSIOLOGY; THERAPEUTICS
- Publication
AYU: An International Quarterly Journal of Research in Ayurveda, 2016, Vol 37, Issue 1, p67
- ISSN
0974-8520
- Publication type
Article
- DOI
10.4103/ayu.AYU_11_16