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- Title
Comparison of ketorolac 0.45% versus diclofenac 0.1% for macular thickness and volume after uncomplicated cataract surgery.
- Authors
Lee, Tae Hee; Choi, Won; Ji, Yong Sok; Yoon, Kyung Chul
- Abstract
Purpose To compare the effects of ketorolac 0.45% and diclofenac 0.1% on macular thickness and volume after uncomplicated cataract surgery. Methods A total of 76 eyes of 76 patients who underwent uncomplicated cataract surgery were included. Patients were treated with either diclofenac 0.1% (38 eyes) or ketorolac 0.45% (38 eyes) after surgery. The macular thickness and volume were obtained with optical coherence tomography ( OCT). Central subfield thickness ( CST, OCT 1 mm zone), total foveal thickness ( TFT, OCT 3 mm zone), total macular thickness ( TMT, OCT 6 mm zone), average macular thickness (AMT) and total macular volume ( TMV) were compared between the two study groups. Results No significant differences between groups were found in macular thickness or volume 1 month after cataract surgery. Two months after surgery, the ketorolac group had significantly lower CST, TFT, TMT and AMT than the diclofenac group (p < 0.05 for all). Additionally, 1 and 2 months after surgery, changes from preoperative values in CST (both p = 0.04), AMT (p = 0.02 and p < 0.01, respectively) and TMV (both p = 0.04) were significantly less in the ketorolac group than in the diclofenac group. Conclusions Following uncomplicated cataract surgery, topical ketorolac 0.45% was more effective than diclofenac 0.1% in preventing increases in macular thickness and volume.
- Subjects
KETOROLAC; DICLOFENAC; CATARACT surgery; SURGICAL complications; OPHTHALMIC surgery; THERAPEUTICS
- Publication
Acta Ophthalmologica (1755375X), 2016, Vol 94, Issue 3, pe177
- ISSN
1755-375X
- Publication type
Article
- DOI
10.1111/aos.12780