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Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.
- Published in:
- Pharmaceutical Research, 2020, v. 37, n. 9, p. N.PAG, doi. 10.1007/s11095-020-02867-z
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- Publication type:
- Article
Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.
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- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 3, p. 209, doi. 10.1002/bdd.2052
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- Publication type:
- Article
Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.
- Published in:
- AAPS Journal, 2016, v. 18, n. 3, p. 589, doi. 10.1208/s12248-016-9889-y
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- Publication type:
- Article
No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in rats.
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- AAPS Journal, 2000, v. 2, n. 3, p. 62, doi. 10.1208/ps020327
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- Publication type:
- Article
Jejunal permeability and hepatic extraction of fluvastatin in humans.
- Published in:
- Clinical Pharmacology & Therapeutics, 1996, v. 60, n. 5, p. 493, doi. 10.1016/S0009-9236(96)90145-9
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- Publication type:
- Article
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.
- Published in:
- 2016
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- Publication type:
- journal article
Single‑Dose Pharmacokinetics and Safety of the Oral Galectin‑3 Inhibitor, Selvigaltin (GB1211), in Participants with Hepatic Impairment.
- Published in:
- Clinical Drug Investigation, 2024, v. 44, n. 10, p. 773, doi. 10.1007/s40261-024-01395-7
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- Publication type:
- Article
A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 10, p. 2392, doi. 10.1111/cts.13368
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- Publication type:
- Article