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- Title
Consistency of data reporting in fluid responsiveness studies in the critically ill setting: the CODEFIRE consensus from the Cardiovascular Dynamic section of the European Society of Intensive Care Medicine.
- Authors
Messina, Antonio; Chew, Michelle S.; Poole, Daniele; Calabrò, Lorenzo; De Backer, Daniel; Donadello, Katia; Hernandez, Glenn; Hamzaoui, Olfa; Jozwiak, Mathieu; Lai, Christopher; Malbrain, Manu L. N. G.; Mallat, Jihad; Myatra, Sheyla Nainan; Muller, Laurent; Ospina-Tascon, Gustavo; Pinsky, Michael R.; Preau, Sebastian; Saugel, Bernd; Teboul, Jean-Louis; Cecconi, Maurizio
- Abstract
Purpose: To provide consensus recommendations regarding hemodynamic data reporting in studies investigating fluid responsiveness and fluid challenge (FC) use in the intensive care unit (ICU). Methods: The Executive Committee of the European Society of Intensive Care Medicine (ESICM) commissioned and supervised the project. A panel of 18 international experts and a methodologist identified main domains and items from a systematic literature, plus 2 ancillary domains. A three-step Delphi process based on an iterative approach was used to obtain the final consensus. In the Delphi 1 and 2, the items were selected with strong (≥ 80% of votes) or week agreement (70–80% of votes), while the Delphi 3 generated recommended (≥ 90% of votes) or suggested (80–90% of votes) items (RI and SI, respectively). Results: We identified 5 main domains initially including 117 items and the consensus finally resulted in 52 recommendations or suggestions: 18 RIs and 2 SIs statements were obtained for the domain "ICU admission", 11 RIs and 1 SI for the domain "mechanical ventilation", 5 RIs for the domain "reason for giving a FC", 8 RIs for the domain pre- and post-FC "hemodynamic data", and 7 RIs for the domain "pre-FC infused drugs". We had no consensus on the use of echocardiography, strong agreement regarding the volume (4 ml/kg) and the reference variable (cardiac output), while weak on administration rate (within 10 min) of FC in this setting. Conclusion: This consensus found 5 main domains and provided 52 recommendations for data reporting in studies investigating fluid responsiveness in ICU patients.
- Subjects
CRITICAL care medicine; CRITICALLY ill; INTENSIVE care units; CARDIAC output; FLUIDS
- Publication
Intensive Care Medicine, 2024, Vol 50, Issue 4, p548
- ISSN
0342-4642
- Publication type
Article
- DOI
10.1007/s00134-024-07344-4