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- Title
Influence of Aerosol Mask Design on Fugitive Aerosol Concentrations During Nebulization.
- Authors
Chen-En Chiang; Hsin-Hsien Li; Daniel D. Rowley; Tien-Pei Fang; Hui-Ling Lin
- Abstract
BACKGROUND: Secondhand exposure to fugitive aerosols may cause airway diseases in health providers. We hypothesized that redesigning aerosol masks to be closed-featured would reduce the fugitive aerosol concentrations during nebulization. This study aimed to evaluate the influence of a mask designed for a jet nebulizer on the concentration of fugitive aerosols and delivered doses. METHODS: An adult intubation manikin was attached to a lung simulator to mimic normal and distressed adult breathing patterns. The jet nebulizer delivered salbutamol as an aerosol tracer. The nebulizer was attached to 3 aerosol face masks: an aerosol mask, a modified non-- rebreathing mask (NRM, with no vent holes), and an AerosoLess mask. An aerosol particle sizer measured aerosol concentrations at parallel distances of 0.8 m and 2.2 m and a frontal distance of 1.8 m from the manikin. The drug dose delivered distal to the manikin's airway was collected, eluted, and analyzed using a spectrophotometer at a 276 nm wavelength. RESULTS: With a normal breathing pattern, the trends of aerosol concentrations were higher with an NRM followed by an aerosol mask and AerosoLess mask (P < .001) at 0.8 m; however, the concentrations were higher with an aerosol mask followed by NRM and AerosoLess mask at 1.8 m (P < .001) and 2.2 m (P < .001). With a distressed breathing pattern, the aerosol concentrations were higher with an aerosol mask followed by an NRM and AerosoLess mask at 0.8 m, 1.8 m (P < .001), and 2.2 m (P 5 .005). The delivered drug dose was significantly higher with AerosoLess mask with a normal breathing pattern and with an aerosol mask with a distressed breathing pattern. CONCLUSIONS: Mask design influences fugitive aerosol concentrations in the environment, and a filtered mask reduces the concentration of aerosols at 3 different distances and with 2 breathing patterns.
- Subjects
RESPIRATORY disease prevention; MEDICAL masks; DRUG delivery systems; KRUSKAL-Wallis Test; AEROSOLS; SPECTROPHOTOMETERS; ALBUTEROL; OCCUPATIONAL exposure; CONTINUING education units; HUMAN anatomical models; SIMULATION methods in education; MANN Whitney U Test; PRODUCT design; NEBULIZERS &; vaporizers; RESPIRATORY therapy; DESCRIPTIVE statistics; RESEARCH funding; INHALATION administration; DATA analysis software; TRACHEA intubation
- Publication
Respiratory Care, 2023, Vol 68, Issue 11, p1510
- ISSN
0020-1324
- Publication type
Article
- DOI
10.4187/respcare.10578