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- Title
Study of aqueous and alcoholic extract of the Coriander effect on Candida albicans.
- Authors
Hasan, Yazdanfar; Yazdanfar, P.; Z., Soedi
- Abstract
Introduction: Fungal infections, especially Candida species, are the most common opportunistic fungal infections and the treatments with chemical drugs have many side effects Coriander antimicrobial effects that have caused it to be considered in many microbial treatments. In this study, it has been tried to compare this herbal efficacy on Candida albicans. Materials and Methods: Aqueous and ethanol extracts of Coriander was obtained by drench method. The diameter of nongrowing zone of C. albicans was estimated by the microdilution method. Result: The mean diameter of the nongrowing zone related to the extracts on C. albicans was 17.83 mm, 20.34mm, 23, 14mm (versing 5.75 mm, 8.45mm, 10, 15mm) of aqueous extracts .in25% and 50% and 75% concentration of Coriander seed extract, ethanol was more effective than distilled water. Conclusion: The research made an experimental and used the coriander seed extract with 3 different concentrations of 25%, 50% and 75% with 2 different solvents (ethanol and distilled water) on C. albicans. The result showed the antifungal effect of the Coriander seed with ethanol was more than distilled water and the cause might be damage of cytoplasmic membrane and subsequent leakage of intercellular compounds such as DNA.
- Subjects
IRAN; ALCOHOLS (Chemical class); CANDIDA albicans; CONFERENCES &; conventions; MEDICINAL plants; PLANT extracts
- Publication
Current Medical Mycology, 2018, Vol 4, p173
- ISSN
2423-3439
- Publication type
Article
- DOI
10.18502/cmm.4.S1.2018.180