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- Title
Long-term deep-TMS does not negatively affect cognitive functions in stroke and spinal cord injury patients with central neuropathic pain.
- Authors
Selingardi, Priscila Mara Lorencini; de Lima Rodrigues, Antonia Lilian; da Silva, Valquíria Aparecida; Fernandes, Diego Toledo Reis Mendes; Rosí, Jefferson; Marcolin, Marco Antônio; Yeng, Lin T.; Brunoni, André R.; Teixeira, Manoel J.; Galhardoni, Ricardo; de Andrade, Daniel Ciampi; Rosí, Jefferson Jr
- Abstract
Conventional superficial transcranial magnetic stimulation (s-TMS) has been studied for the treatment of several neuropsychiatric disorders for the last two decades [[1]]. For these patients, new non-invasive cortical stimulation approaches have been proposed, such as deep-TMS (d-TMS). d-TMS allows for the stimulation of deeper cortical structures such as the dentate nucleus of the cerebellum [[13]], the insular [[14]] and the cingulate cortices [[15]], or the leg areas of the primary motor cortex [[12], [16]]. While several studies have reported on the safety of s-TMS in psychiatric and neurological disorders [[9], [47]-[49]], few have included more than 25 patients per arm [[9], [50]-[52]], and the vast majority of them evaluated the effects of s-TMS targeted to the dorsolateral prefrontal cortex [[47]-[49], [51], [53]-[61]], as this is a common superficial target in major depression treatment trials.
- Subjects
SPINAL cord injuries; COGNITIVE ability; TRANSCRANIAL magnetic stimulation; WISCONSIN Card Sorting Test; WECHSLER Adult Intelligence Scale
- Publication
BMC Neurology, 2019, Vol 19, Issue 1, p1
- ISSN
1471-2377
- Publication type
journal article
- DOI
10.1186/s12883-019-1531-z