We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Incorporation of Indole Significantly Improves the Transfection Efficiency of Guanidinium‐Containing Poly(Methacrylamide)s.
- Authors
Cokca, Ceren; Zartner, Leon; Tabujew, Ilja; Fischer, Dagmar; Peneva, Kalina
- Abstract
Incorporation of Indole Significantly Improves the Transfection Efficiency of Guanidinium-Containing Poly(Methacrylamide)s B Front Cover b : In article 1900668 by Dagmar Fischer, Kalina Peneva, and co-workers, the incorporation of indole-based monomers in guanidinium-containing poly(methacrylamide)s leads to highly efficient transfection agents that can condense plasmid DNA even at a nitrogen-to-phosphate (N/P) ratio of 1 and show a 200-fold increase in transfection compared to their guanidinium counterparts. The strong potential of the indole group as a side-chain functionality to increase cellular uptake of polymers is also demonstrated.
- Subjects
GENE transfection; INDOLE; POLYETHYLENEIMINE; MONOMERS; ACRYLAMIDE; POLYMERS
- Publication
Macromolecular Rapid Communications, 2020, Vol 41, Issue 6, p1
- ISSN
1022-1336
- Publication type
Article
- DOI
10.1002/marc.201900668