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The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2.
Published in:
Molecules, 2022, v. 27, n. 13, p. 4212, doi. 10.3390/molecules27134212
By:
- Feng, Joy Y.;
- Du Pont, Venice;
- Babusis, Darius;
- Gordon, Calvin J.;
- Tchesnokov, Egor P.;
- Perry, Jason K.;
- Duong, Vincent;
- Vijjapurapu, Arya;
- Zhao, Xiaofeng;
- Chan, Julie;
- Cohen, Cal;
- Juneja, Kavita;
- Cihlar, Tomas;
- Götte, Matthias;
- Bilello, John P.
Publication type:
Article
Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.
Published in:
PLoS Neglected Tropical Diseases, 2020, v. 14, n. 6, p. 1, doi. 10.1371/journal.pntd.0008283
By:
- Tchesnokov, Egor P.;
- Bailey-Elkin, Ben A.;
- Mark, Brian L.;
- Götte, Matthias
Publication type:
Article
Efficient Incorporation and Template‐Dependent Polymerase Inhibition are Major Determinants for the Broad‐Spectrum Antiviral Activity of Remdesivir.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4278
By:
- Gordon, Calvin J.;
- Lee, Hery W.;
- Tchesnokov, Egor P.;
- Perry, Jason K.;
- Feng, Joy Y.;
- Bilello, John P.;
- Porter, Danielle P.;
- Gotte, Matthias
Publication type:
Article
Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir.
Published in:
Viruses (1999-4915), 2019, v. 11, n. 4, p. 326, doi. 10.3390/v11040326
By:
- Tchesnokov, Egor P.;
- Feng, Joy Y.;
- Porter, Danielle P.;
- Götte, Matthias
Publication type:
Article
Sandacrabins – Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium**.
Published in:
Chemistry - A European Journal, 2022, v. 28, n. 11, p. 1, doi. 10.1002/chem.202104484
By:
- Bader, Chantal D.;
- Panter, Fabian;
- Garcia, Ronald;
- Tchesnokov, Egor P.;
- Haid, Sibylle;
- Walt, Christine;
- Spröer, Cathrin;
- Kiefer, Alexander F.;
- Götte, Matthias;
- Overmann, Jörg;
- Pietschmann, Thomas;
- Müller, Rolf
Publication type:
Article
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms.
Published in:
Science Translational Medicine, 2022, v. 14, n. 656, p. 1, doi. 10.1126/scitranslmed.abo0718
By:
- Stevens, Laura J.;
- Pruijssers, Andrea J.;
- Lee, Hery W.;
- Gordon, Calvin J.;
- Tchesnokov, Egor P.;
- Gribble, Jennifer;
- George, Amelia S.;
- Hughes, Tia M.;
- Lu, Xiaotao;
- Li, Jiani;
- Perry, Jason K.;
- Porter, Danielle P.;
- Cihlar, Tomas;
- Sheahan, Timothy P.;
- Baric, Ralph S.;
- Götte, Matthias;
- Denison, Mark R.
Publication type:
Article
Evolution of naturally arising SARS-CoV-2 defective interfering particles.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04058-5
By:
- Girgis, Samer;
- Xu, Zaikun;
- Oikonomopoulos, Spyros;
- Fedorova, Alla D.;
- Tchesnokov, Egor P.;
- Gordon, Calvin J.;
- Schmeing, T. Martin;
- Götte, Matthias;
- Sonenberg, Nahum;
- Baranov, Pavel V.;
- Ragoussis, Jiannis;
- Hobman, Tom C.;
- Pelletier, Jerry
Publication type:
Article

Found: 7

The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2.

Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.

Efficient Incorporation and Template‐Dependent Polymerase Inhibition are Major Determinants for the Broad‐Spectrum Antiviral Activity of Remdesivir.

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir.

Sandacrabins – Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium**.

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms.

Evolution of naturally arising SARS-CoV-2 defective interfering particles.