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- Title
Refractory Fetal Supraventricular Tachycardia and Obstetric Cholestasis.
- Authors
Shand, Antonia W.; Dickinson, Jan E.; D'Orsogna, Luigi
- Abstract
Objective: Supraventricular tachycardia (SVT) is the most common form of sustained fetal tachyarrhythmia in pregnancy. The development of hydrops with SVT is associated with significant worsening of prognosis. Case: We report a case of fetal SVT with hydrops at 28 weeks’ gestation that required both transplacental and direct fetal treatment in a woman with concurrent obstetric cholestasis. Antiarrhythmic therapy and control of the maternal liver function and bile acid levels with ursodeoxycholic acid was associated with a fetal response to treatment resulting in a healthy term live birth. Conclusion: Fetal SVT and hydrops fetalis are associated with significant perinatal morbidity and mortality. Resistance to intensive antiarrhythmic therapies may be augmented by the myocardial effects of obstetric cholestasis and remains a challenge for management. Copyright © 2008 S. Karger AG, Basel
- Subjects
TACHYCARDIA; ARRHYTHMIA; CHOLESTASIS; OBSTRUCTIVE jaundice; HEART beat
- Publication
Fetal Diagnosis & Therapy, 2008, Vol 24, Issue 3, p277
- ISSN
1015-3837
- Publication type
Article
- DOI
10.1159/000151676