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- Title
First-in-children epicardial mapping of the heart: unravelling arrhythmogenesis in congenital heart disease.
- Authors
Kharbanda, Rohit K; Schie, Mathijs S van; Leeuwen, Wouter J van; Taverne, Yannick J.H.J; Houck, Charlotte A; Kammeraad, Janneke A.E; Bogers, Ad J.J.C; Groot, Natasja M.S de
- Abstract
Patients with congenital heart disease (CHD) are prone to develop atrial and ventricular arrhythmias. Multiple factors throughout life contribute to arrhythmogenicity substrate such as (i) (longstanding) volume and/or pressure overload, (ii) scar tissue, (iii) ageing-related structural remodelling, (iv) cardiovascular risk factors and (v) tachycardia-induced remodelling. At present, it is unknown whether, and to what extent, paediatric patients with CHD have atrial or ventricular conduction disorders early in life and whether there is a correlation between duration of volume/pressure overload and extensiveness of conduction disorders. To investigate this, we initiated high-resolution intraoperative epicardial mapping in paediatric patients with CHD undergoing primary open-heart surgery.
- Publication
Interactive Cardiovascular & Thoracic Surgery, 2021, Vol 32, Issue 1, p137
- ISSN
1569-9293
- Publication type
Article
- DOI
10.1093/icvts/ivaa233