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- Title
Application of Extracellular Vesicles in Gynecologic Cancer Treatment.
- Authors
Zhang, Renwen; Zou, Yixing; Luo, Jing
- Abstract
Ovarian, cervical, and endometrial cancer are the three most common gynecological malignancies that seriously threaten women's health. With the development of molecular biology technology, immunotherapy and targeted therapy for gynecologic tumors are being carried out in clinical treatment. Extracellular vesicles are nanosized; they exist in various body fluids and play an essential role in intercellular communication and in the regulation of various biological process. Several studies have shown that extracellular vesicles are important targets in gynecologic cancer treatment as they promote tumor growth, progression, angiogenesis, metastasis, chemoresistance, and immune system escape. This article reviews the progress of research into extracellular vesicles in common gynecologic tumors and discusses the role of extracellular vesicles in gynecologic tumor treatment.
- Subjects
EXTRACELLULAR vesicles; GYNECOLOGIC cancer; NEOVASCULARIZATION; REGULATION of body fluids; CANCER treatment; DEVELOPMENTAL biology; MOLECULAR biology
- Publication
Bioengineering (Basel), 2022, Vol 9, Issue 12, p740
- ISSN
2306-5354
- Publication type
Article
- DOI
10.3390/bioengineering9120740