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- Title
Re: Modification of Clinical Presentation of Prostate Tumors by a Novel Genetic Variant in CYP3A4.
- Authors
Wojnowski, Leszek; Hustert, Elisabeth; Klein, Kathrin; Goldammer, Mark; Haberl, Michael; Kirchheiner, Julia; Koch, Ina; Klattig, Jürgen; Zanger, Ulrich; Brockmöller, Jürgen
- Abstract
Presents correspondence on the clinical modification of prostate tumors by novel genetic variant in CYP3A4. Observation on the CYP3A4 isozymes in liver biopsy specimens; Reduction on the risk for treatment-related leukemia; Effects on the production of DNA-damaging chemotherapeutic metabolites.
- Subjects
PROSTATE cancer; HUMAN genetic variation
- Publication
JNCI: Journal of the National Cancer Institute, 2002, Vol 94, Issue 8, p631
- ISSN
0027-8874
- Publication type
Article
- DOI
10.1093/jnci/94.8.630