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- Title
Trends in Enantioselective High Performance Liquid Chromatography.
- Authors
Woiwode, Ulrich; Neubauer, Stefan; Kaupert, Mike; Lindner, Wolfgang; Lämmerhofer, Michael
- Abstract
Enantioselective high performance liquid chromatography (HPLC) is slowly adopting the modern particle technologies (sub-2-µm fully porous particles [FPPs] and sub-3-pm superficially porous silica particles [SPPs]) that have been well known in reversed-phase LC for the past decade. The most significant benefit is that enantiomer separations can be performed much faster, which is of interest in high-throughput screening applications and multidimensional enantioselective HPLC analysis. The state of the art is briefly discussed with some examples documenting the potential of core-shell particle technology and comprehensive multidimensional separations.
- Subjects
HIGH performance liquid chromatography; ENANTIOSELECTIVE catalysis; SEPARATION of enantiomers; POROSITY; PARTICLES
- Publication
LC-GC Europe, 2017, Vol 30, p34
- ISSN
1471-6577
- Publication type
Article